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Case Series of Cancer-associated Retinopathy (CAR)

Identifieur interne : 004026 ( Main/Exploration ); précédent : 004025; suivant : 004027

Case Series of Cancer-associated Retinopathy (CAR)

Auteurs :

Source :

RBID : PMC:6687430

Abstract

Cancer-associated retinopathy (CAR) is a rare paraneoplastic disorder of the retina leading to blindness, associated with multiple cancers. It can lead to rapid progressive visual deterioration with retinal pathology ranging from retinitis pigmentosa to retinal degeneration. It is caused by antibodies directed against retinal antigens. This uncommon syndrome is a remote effect, independent of the primary tumor or metastatic lesion. We describe two cases of CAR, as well as pathophysiology, clinical manifestation, diagnostic criteria, and treatment of cancer-associated retinopathy.


Url:
DOI: 10.7759/cureus.4872
PubMed: 31417817
PubMed Central: 6687430


Affiliations:


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Le document en format XML

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<p>Cancer-associated retinopathy (CAR) is a rare paraneoplastic disorder of the retina leading to blindness, associated with multiple cancers. It can lead to rapid progressive visual deterioration with retinal pathology ranging from retinitis pigmentosa to retinal degeneration. It is caused by antibodies directed against retinal antigens. This uncommon syndrome is a remote effect, independent of the primary tumor or metastatic lesion. We describe two cases of CAR, as well as pathophysiology, clinical manifestation, diagnostic criteria, and treatment of cancer-associated retinopathy.</p>
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